Author:
Sahafi A.,Wang Y.,Rasmussen C. L. M.,Bollen P.,Baatrup G.,Blanes-Vidal V.,Herp J.,Nadimi E. S.
Abstract
AbstractGastrointestinal (GI) tract diseases are responsible for substantial morbidity and mortality worldwide, including colorectal cancer, which has shown a rising incidence among adults younger than 50. Although this could be alleviated by regular screening, only a small percentage of those at risk are screened comprehensively, due to shortcomings in accuracy and patient acceptance. To address these challenges, we designed an artificial intelligence (AI)-empowered wireless video endoscopic capsule that surpasses the performance of the existing solutions by featuring, among others: (1) real-time image processing using onboard deep neural networks (DNN), (2) enhanced visualization of the mucous layer by deploying both white-light and narrow-band imaging, (3) on-the-go task modification and DNN update using over-the-air-programming and (4) bi-directional communication with patient’s personal electronic devices to report important findings. We tested our solution in an in vivo setting, by administrating our endoscopic capsule to a pig under general anesthesia. All novel features, successfully implemented on a single platform, were validated. Our study lays the groundwork for clinically implementing a new generation of endoscopic capsules, which will significantly improve early diagnosis of upper and lower GI tract diseases.
Funder
Aage og Johanne Louis-Hansens Fond
Syddansk Universitet
Publisher
Springer Science and Business Media LLC
Reference37 articles.
1. Bujanda, L., Cosme, A., Gil, I. & Arenas-Mirave, J. I. Malignant colorectal polyps. World J. Gastroenterol. 25, 3103–3111 (2010).
2. Colorectal cancer facts & figures 2020-2022. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/colorectal-cancer-facts-and-figures/colorectal-cancer-facts-and-figures-2020-2022.pdf.
3. Lee, J. K., Liles, E. G., Bent, S., Levin, T. R. & Corley, D. A. Accuracy of fecal immunochemical tests for colorectal cancer: Systematic review and meta-analysis. Annals Intern. Med. 160, 171. https://doi.org/10.7326/M13-1484 (2014).
4. Gorard, D. A. & McIntyre, A. S. Completion rate to caecum as a quality measure of colonoscopy in a district general hospital. Colorectal Dis. 6, 243–249. https://doi.org/10.1111/j.1463-1318.2004.00628.x (2004).
5. Hendry, P. O., Jenkins, J. T. & Diament, R. H. The impact of poor bowel preparation on colonoscopy: A prospective single centre study of 10571 colonoscopies. Colorectal Dis. 9, 745–748. https://doi.org/10.1111/j.1463-1318.2004.00628.x (2007).
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