Author:
Yamazaki Yoshio,Sugisaki Kenji,Araie Makoto,Murata Hiroshi,Kanamori Akiyasu,Inoue Toshihiro,Ishikawa Shinichiro,Yoshikawa Keiji,Maeda Hidetaka,Yamada Yuko,Negi Akira,Inatani Masaru,Tanihara Hidenobu,Okinami Satoshi,Mizuki Kenji,Mishima Koichi,Uchida Kenichi,Matsumoto Shun
Abstract
Abstract
To investigate the relationships between sensitivity loss in various subfields of the central 10° of the binocular integrated visual field (IVF) and vision-related quality of life (VRQoL) in 172 patients with advanced glaucoma. Using the Random Forest algorithm, which controls for inter-correlations among various subfields of the IVF, we analysed the relationships among the Rasch analysis-derived person ability index (RADPAI), age, best-corrected visual acuity (BCVA), mean total deviations (mTDs) of eight quadrant subfields in the IVF measured with the Humphrey Field Analyzer (HFA) 10-2 program (10-2 IVF), and mTDs of the upper/lower hemifields in the IVF measured with the HFA 24-2 program (24-2 IVF). Significant contributors to RADPAIs were as follows: the inner and outer lower-right quadrants of the 10-2 IVF contributed to the dining and total tasks; the lower-left quadrant of the 10-2 IVF contributed to the walking, going out and total tasks; the lower hemifield of the 24-2 IVF contributed to the walking, going out, dining, miscellaneous and total tasks; and BCVA contributed more to the letter, sentence, dressing and miscellaneous tasks than to others. The impact of damage in different 10-2 IVF subfields differed significantly across daily tasks in patients with advanced glaucoma.
Publisher
Springer Science and Business Media LLC
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