Global view of the RAF-MEK-ERK module and its immediate downstream effectors-Reference-Cited by-同舟云学术

Global view of the RAF-MEK-ERK module and its immediate downstream effectors

Published:2019-07-26 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Santini Cristina C.^ORCID,Longden James,Schoof Erwin M.,Simpson Craig D.^ORCID,Jeschke Grace R.^ORCID,Creixell Pau,Kim Jinho^ORCID,Wu Xuewei,Turk Benjamin E.,Rosen Neal,Poulikakos Poulikos I.,Linding Rune

Funder

Independent Research Fund Denmark

Lundbeckfonden

Sapere Aude Fellowship, Independent Research Fund Denmark

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-47245-x.pdf

Reference48 articles.

1. Shaul, Y. D. & Seger, R. The MEK/ERK cascade: From signaling specificity to diverse functions. Biochim Biophys Acta 1773(8), 1213–1226 (2007).

2. Roberts, P. J. & Der, C. J. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26(22), 3291–3310 (2007).

3. Lavoie, H. & Therrien, M. Regulation of RAF protein kinases in ERK signalling. Nat Rev Mol Cell Biol 16(5), 281–298 (2015).

4. Davies, H. et al. Mutations of the BRAF gene in human cancer. Nature 417, 949–954 (2002).

5. Ascierto, P. A. et al. The role of BRAF V600 mutation in melanoma. J Transl Med 10, 85 (2012).

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