Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes

Author:

Fenclova MarieORCID,Novakova Alena,Viktorova Jitka,Jonatova Petra,Dzuman Zbynek,Ruml Tomas,Kren Vladimir,Hajslova Jana,Vitek LiborORCID,Stranska-Zachariasova Milena

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference57 articles.

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3. Smith, T., Kawa, K., Eckl, V., Morton, C. & Stredney, R. Herbal Supplement Sales in US Increase 7.7% in 2016 Consumer preferences shifting toward ingredients with general wellness benefits, driving growth of adaptogens and digestive health products. HerbalGram 115, 56–65 (2017).

4. Kim, N. C., Graf, T. N., Sparacino, C. M., Wani, M. C. & Wall, M. E. Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum). Org Biomol Chem 1, 1684–1689 (2003).

5. Skottova, N. et al. Effects of polyphenolic fraction of silymarin on lipoprotein profile in rats fed cholesterol-rich diets. Pharmacol Res 47, 17–26 (2003).

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