Author:
Sorokina Oksana,Mclean Colin,Croning Mike D. R.,Heil Katharina F.,Wysocka Emilia,He Xin,Sterratt David,Grant Seth G. N.,Simpson T. Ian,Armstrong J. Douglas
Abstract
AbstractGenes encoding synaptic proteins are highly associated with neuronal disorders many of which show clinical co-morbidity. We integrated 58 published synaptic proteomic datasets that describe over 8000 proteins and combined them with direct protein–protein interactions and functional metadata to build a network resource that reveals the shared and unique protein components that underpin multiple disorders. All the data are provided in a flexible and accessible format to encourage custom use.
Publisher
Springer Science and Business Media LLC