Ormeloxifene-induced unfolded protein response contributes to autophagy-associated apoptosis via disruption of Akt/mTOR and activation of JNK
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-20541-8.pdf
Reference54 articles.
1. American Cancer Society. Cancer Facts & Figs 2015. Atlanta: American Cancer Society (2015).
2. Misra, N. C., Nigam, P. K., Gupta, R., Agarwal, A. K. & Kamboj, V. P. Centchroman–a non-steroidal anti-cancer agent for advanced breast cancer: phase-II study. Int J Cancer 43(5), 781–3 (1989).
3. Nigam, M., Ranjan, V., Srivastava, S., Sharma, R. & Balapure, A. K. Centchroman induces G0/G1 arrest and caspase-dependent apoptosis involving mitochondrial membrane depolarization in MCF-7 and MDA MB-231 human breast cancer cells. Life Sci. 82, 577–90 (2008).
4. Srivastava, V. K., Gara, R. K., Bhatt, M. L. B., Sahu, D. P. & Mishra, D. P. Centchroman inhibits proliferation of head and neck cancer cells through the modulation of PI3K/mTOR pathway. Biochem. Biophys. Res. Commun. 404, 40–5 (2011).
5. Pal, P. et al. 2-D gel electrophoresis-based proteomic analysis reveals that ormeloxifen induces G0-G1 growth arrest and ERK-mediated apoptosis in chronic myeloid leukemia cells K562. Proteomics 11, 1517–29 (2011).
Cited by 28 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Immobilized doxorubicin and ribociclib carbamate linkers encaged in surface modified cubosomes spatially target tumor reductive environment to enhance antitumor efficacy;Biomaterials Advances;2023-12
2. Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA;Basic Research in Cardiology;2023-11-03
3. CLUH functions as a negative regulator of inflammation in human macrophages and determines ulcerative colitis pathogenesis;JCI Insight;2023-06-08
4. Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizingCluhandSmyd1mRNA;2023-03-02
5. Inhibition of Autophagy Increases Cell Death in HeLa Cells through Usnic Acid Isolated from Lichens;Plants;2023-01-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3