Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression-Reference-Cited by-同舟云学术

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Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression

Published:2019-08-06 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Hughes Jennifer,Surakhy Mirvat^ORCID,Can Sermet,Ducker Martin,Davies Nick,Szele Francis,Bühnemann Claudia,Carter Emma^ORCID,Trikin Roman,Crump Matthew P.^ORCID,Frago Susana,Hassan A. Bassim

Funder

Clarendon Arab Bank

EPA research fund

Oxford Doctoral Training Centre

RCUK | Medical Research Council

Cancer Research UK

Clarendon Arab Bank (MS) Oxford Doctoral Training Centre (MD) EPA research trust

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-47827-9.pdf

Reference73 articles.

1. Ghosh, P., Dahms, N. M. & Kornfeld, S. Mannose 6-phosphate receptors: new twists in the tale. Nat Rev Mol Cell Biol 4, 202–212 (2003).

2. Williams, C. et al. An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Science 338, 1209–1213 (2012).

3. Haig, D. & Graham, C. Genomic imprinting and the strange case of the insulin-like growth factor II receptor. Cell 64, 1045–1046 (1991).

4. Barlow, D. P., Stoger, R., Herrmann, B. G., Saito, K. & Schweifer, N. The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature 349, 84–87 (1991).

5. Eggenschwiler, J. et al. Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. Genes Dev 11, 3128–3142 (1997).

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