Interplay of Darwinian Selection, Lamarckian Induction and Microvesicle Transfer on Drug Resistance in Cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-45863-z.pdf
Reference62 articles.
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2. Gerlinger, M. & Swanton, C. How darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine. Br. J. Cancer 103, 1139–1143, https://doi.org/10.1038/sj.bjc.6605912 (2010).
3. Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: The next generation. Cell 144, 646–674, https://doi.org/10.1016/j.cell.2011.02.013 (2011).
4. Gillies, R. J., Verduzco, D. & Gatenby, R. A. Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat. Rev. Cancer 12, 487–493, https://doi.org/10.1038/nrc3298 (2012).
5. Easwaran, H., Tsai, H.-C. & Baylin, S. B. Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. Mol. Cell 54, 716–727, https://doi.org/10.1016/j.molcel.2014.05.015 (2014).
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