L290P/V mutations increase ERK3’s cytoplasmic localization and migration/invasion-promoting capability in cancer cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-15135-9.pdf
Reference27 articles.
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3. Julien, C., Coulombe, P. & Meloche, S. Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression. J Biol Chem 278, 42615–24 (2003).
4. Al-Mahdi, R. et al. A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration. Cell Adh Migr 9, 483–94 (2015).
5. Seternes, O. M. et al. Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway. Embo J 23, 4780–91 (2004).
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