Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-07567-0.pdf
Reference18 articles.
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2. Nuriel-Ohayon, M., Neuman, H. & Koren, O. Microbial Changes during Pregnancy, Birth, and Infancy. Front. Microbiol. 7, 1031 (2016).
3. Faber, F. et al. Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion. Nature 534, 697–699 (2016).
4. Li, W. et al. Promysalin, a salicylate-containing Pseudomonas putida antibiotic, promotes surface colonization and selectively targets other Pseudomonas. Chem. Biol. 18, 1320–1330 (2011).
5. Steele, A. D., Knouse, K. W., Keohane, C. E. & Wuest, W. M. Total synthesis and biological investigation of (−)-promysalin. J. Am. Chem. Soc. 137, 7314–7317 (2015).
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