Apicomplexan actin polymerization depends on nucleation

Author:

Kumpula Esa-Pekka,Pires IsaORCID,Lasiwa Devaki,Piirainen Henni,Bergmann Ulrich,Vahokoski Juha,Kursula InariORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference41 articles.

1. Sept, D. & McCammon, J. A. Thermodynamics and kinetics of actin filament nucleation. Biophys. J. 81, 667–674 (2001).

2. Cooper, J. A., Buhle, E. L., Walker, S. B., Tsong, T. Y. & Pollard, T. D. Kinetic evidence for a monomer activation step in actin polymerization. Biochemistry 22, 2193–2202 (1983).

3. Tobacman, L. S. & Korn, E. D. The kinetics of actin nucleation and polymerization. J. Biol. Chem. 258, 3207–3214 (1983).

4. Pollard, T. D. Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments. J. Cell Biol. 103, 2747–2754 (1986).

5. Kumpula, E. P. & Kursula, I. Towards a molecular understanding of the apicomplexan actin motor: On a road to novel targets for malaria remedies? Acta Crystallogr. F 71, 500–513 (2015).

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