Identification of a gene cluster for telomestatin biosynthesis and heterologous expression using a specific promoter in a clean host
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-03308-5.pdf
Reference33 articles.
1. Shin-ya, K. et al. Telomestatin, a Novel Telomerase Inhibitor from Streptomyces anulatus. J. Am. Chem. Soc. 123, 1262–1263 (2001).
2. Kim, M.-Y., Vankayalapati, H., Shin-ya, K., Wierzba, K. & Hurley, L. H. Telomestatin, a Potent Telomerase Inhibitor That Interacts Quite Specifically with the Human Telomeric Intramolecular G-Quadruplex. J. Am. Chem. Soc. 124, 2098–2099 (2002).
3. Tauchi, T. et al. Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways. Oncogene 22, 5338–5347 (2003).
4. Tauchi, T. et al. Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia. Oncogene 25, 5719–5725 (2006).
5. Wu, Y. et al. Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. Blood 116, 3780–3791 (2010).
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