Pharmacologic targeting of β-catenin improves fracture healing in old mice
Author:
Funder
U.S. Department of Health & Human Services | NIH | National Institute on Aging
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-45339-0.pdf
Reference29 articles.
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2. Hak, D. J. et al. Delayed union and nonunions: epidemiology, clinical issues, and financial aspects. Injury 45(Suppl 2), S3–7, https://doi.org/10.1016/j.injury.2014.04.002 (2014).
3. Lu, C. et al. Cellular basis for age-related changes in fracture repair. J Orthop Res 23, 1300–1307, https://doi.org/10.1016/j.orthres.2005.04.003.1100230610 (2005).
4. Meyer, R. A. Jr. et al. Age and ovariectomy impair both the normalization of mechanical properties and the accretion of mineral by the fracture callus in rats. J Orthop Res 19, 428–435, https://doi.org/10.1016/S0736-0266(00)90034-2 (2001).
5. Gruber, R. et al. Fracture healing in the elderly patient. Exp Gerontol 41, 1080–1093, https://doi.org/10.1016/j.exger.2006.09.008 (2006).
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