LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm.4076.pdf
Reference44 articles.
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2. Hanada, R., Hanada, T., Sigl, V., Schramek, D. & Penninger, J.M. RANKL/RANK-beyond bones. J. Mol. Med. 89, 647–656 (2011).
3. Fata, J.E. et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell 103, 41–50 (2000).
4. Jones, D.H. et al. Regulation of cancer cell migration and bone metastasis by RANKL. Nature 440, 692–696 (2006).
5. Gonzalez-Suarez, E. et al. RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. Nature 468, 103–107 (2010).
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