Metabolic barriers to cancer immunotherapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
https://www.nature.com/articles/s41577-021-00541-y.pdf
Reference201 articles.
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4. Ho, P.-C. et al. Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses. Cell 162, 1217–1228 (2015). This study shows the mechanism by which glucose deprivation in the tumour can restrict antitumour T cell activity.
5. Chang, C.-H. et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 153, 1239–1251 (2013).
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