Building better monoclonal antibody-based therapeutics
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/nrc3930.pdf
Reference114 articles.
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3. Kohler, G. & Milstein, C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495 (1975). This landmark publication outlines how to produce mAbs, as well as their therapeutic potential.
4. Milstein, C. From the structure of antibodies to the diversification of the immune response. Nobel lecture, 8 December 1984. Biosci. Rep. 5, 275–297 (1985).
5. Bernard, A. & Boumsell, L. The clusters of differentiation (CD) defined by the First International Workshop on Human Leucocyte Differentiation Antigens. Hum. Immunol. 11, 1–10 (1984).
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