ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2012362.pdf
Reference51 articles.
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3. Robertson KA, Emami B, Mueller L, Collins SJ . Multiple members of the retinoic acid receptor family are capable of mediating the granulocytic differentiation of HL-60 cells. Mol Cell Biol 1992; 12: 3743–3749.
4. Purton LE, Bernstein ID, Collins SJ . All-trans retinoic acid delays the differentiation of primitive hematopoietic precursors (lin-c-kit+Sca-1(+)) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors. Blood 1999; 94: 483–495.
5. Zhu J, Heyworth CM, Glasow A, Huang QH, Petrie K, Lanotte M et al. Lineage restriction of the RARalpha gene expression in myeloid differentiation. Blood 2001; 98: 2563–2567.
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