Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
Author:
Publisher
Springer Science and Business Media LLC
Subject
Computer Science Applications,Biomedical Engineering,Medicine (miscellaneous),Bioengineering,Biotechnology
Link
http://www.nature.com/articles/s41551-019-0498-9.pdf
Reference68 articles.
1. Shanks, N., Greek, R. & Greek, J. Are animal models predictive for humans? Philos. Ethics Humanit. Med. 4, 2 (2009).
2. Malinowski, H. et al. Draft guidance for industry extended-release solid oral dosage forms. Development, evaluation and application of in vitro-in vivo correlations. Adv. Exp. Med. Biol. 423, 269–288 (1997).
3. Danhof, M., de Lange, E. C. M., Della Pasqua, O. E., Ploeger, B. A. & Voskuyl, R. A. Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research. Trends Pharmacol. Sci. 29, 186–191 (2008).
4. Abaci, H. E. & Shuler, M. L. Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling. Integr. Biol. 7, 383–391 (2015).
5. Esch, M. B., Ueno, H., Applegate, D. R. & Shuler, M. L. Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue. Lab Chip 16, 2719–2729 (2016).
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