Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

Author:

Akinc Akin,Goldberg Michael,Qin June,Dorkin J Robert,Gamba-Vitalo Christina,Maier Martin,Jayaprakash K Narayanannair,Jayaraman Muthusamy,Rajeev Kallanthottathil G,Manoharan Muthiah,Koteliansky Victor,Röhl Ingo,Leshchiner Elizaveta S,Langer Robert,Anderson Daniel G

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference41 articles.

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2. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs;Soutschek;Nature,2004

3. Interfering with disease: a progress report on siRNA-based therapeutics;de Fougerolles;Nat Rev Drug Discov,2007

4. The RNAi revolution;Novina;Nature,2004

5. Gene therapy put on hold as third child develops cancer;Check;Nature,2005

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