Combining Chemical Profiling and Network Analysis to Investigate the Pharmacology of Complex Prescriptions in Traditional Chinese Medicine

Author:

Suo Tongchuan,Liu Jinping,Chen Xi,Yu Hua,Wang Tenglong,Li Congcong,Wang Yuefei,Wang Chunhua,Li Zheng

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference34 articles.

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2. Hopkins, A. L. Network pharmacology: the next paradigm in drug discovery. Nat. Chem. Biol. 4, 682–690 (2008).

3. Wang, L. et al. A network study of Chinese medicine Xuesaitong injection to elucidate a complex mode of action with multicompound, multitarget, and multipathway. Evid.-based Complement Altern. Med. 2013, 652373 (2013).

4. Wang, L. et al. Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network. Mol. BioSyst. 10, 1905–1911 (2014).

5. Yang, Z.-Z., Liu, W., Zhang, F., Li, Z. & Cheng, Y.-Y. Deciphering the therapeutic mechanisms of Xiao-Ke-An in treatment of type 2 diabetes in mice by a fangjiomics approach. Acta Pharmacol. Sin. 36, 699 (2015).

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