Epac: a new cAMP target and new avenues in cAMP research
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm1197.pdf
Reference42 articles.
1. Alberts, B. et al. Molecular Biology of the Cell 4th edn (Garland Science, New York, 2002).
2. de Rooij, J. et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 396, 474–477 (1998).
3. de Rooij, J. et al. Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs. J. Biol. Chem. 275, 20829–20836 (2000).
4. Kawasaki, H. et al. A family of cAMP-binding proteins that directly activate Rap1. Science 282, 2275–2279 (1998).
5. Rehmann, H. et al. Structure and regulation of the cAMP-binding domains of Epac2. Nature Struct. Biol. 10, 26–32 (2003).
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