A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity
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Published:2021-02-25
Issue:4
Volume:27
Page:659-667
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ISSN:1078-8956
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Container-title:Nature Medicine
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language:en
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Short-container-title:Nat Med
Author:
Zhou Sirui, Butler-Laporte GuillaumeORCID, Nakanishi TomokoORCID, Morrison David R.ORCID, Afilalo Jonathan, Afilalo Marc, Laurent Laetitia, Pietzner Maik, Kerrison Nicola, Zhao Kaiqiong, Brunet-Ratnasingham ElsaORCID, Henry Danielle, Kimchi Nofar, Afrasiabi ZamanORCID, Rezk NardinORCID, Bouab Meriem, Petitjean LouisORCID, Guzman CharlotteORCID, Xue Xiaoqing, Tselios Chris, Vulesevic Branka, Adeleye Olumide, Abdullah Tala, Almamlouk Noor, Chen Yiheng, Chassé Michaël, Durand Madeleine, Paterson Clare, Normark Johan, Frithiof RobertORCID, Lipcsey Miklós, Hultström MichaelORCID, Greenwood Celia M. T.ORCID, Zeberg Hugo, Langenberg ClaudiaORCID, Thysell Elin, Pollak Michael, Mooser Vincent, Forgetta Vincenzo, Kaufmann Daniel E.ORCID, Richards J. BrentORCID
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference63 articles.
1. Johns Hopkins University of Medicine. Coronavirus Resource Center. https://coronavirus.jhu.edu/ (2020). 2. Weinreich, D. M. et al. REGN-COV2, a neutralizing antibody cocktail, in outpatients with Covid-19. N. Engl. J. Med. 384, 238–251 (2020). 3. Horby, P. et al. Dexamethasone in hospitalized patients with Covid-19—preliminary report. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2021436 (2020). 4. Sterne, J. A. C. et al. Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis. JAMA 324, 1330–1341 (2020). 5. Beigel, J. H., Tomashek, K. M. & Dodd, L. E. Remdesivir for the treatment of Covid-19—preliminary report. N. Engl. J. Med. 383, 994 (2020).
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