A fully human transgene switch to regulate therapeutic protein production by cooling sensation
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/s41591-019-0501-8.pdf
Reference52 articles.
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3. Lanitis, E. et al. Redirected antitumor activity of primary human lymphocytes transduced with a fully human anti-mesothelin chimeric receptor. Mol. Ther. 20, 633–643 (2012).
4. Le Guiner, C., Stieger, K., Snyder, R. O., Rolling, F. & Moullier, P. Immune responses to gene product of inducible promoters. Curr. Gene Ther. 7, 334–346 (2007).
5. Maus, M. V. et al. T cells expressing chimeric antigen receptors can cause anaphylaxis in humans. Cancer Immunol. Res. 1, 26–31 (2013).
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