Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination

Author:

Cheng Samuel M. S.,Mok Chris Ka PunORCID,Leung Yonna W. Y.,Ng Susanna S.,Chan Karl C. K.,Ko Fanny W.,Chen Chunke,Yiu Karen,Lam Bosco H. S.,Lau Eric H. Y.ORCID,Chan Ken K. P.,Luk Leo L. H.,Li John K. C.,Tsang Leo C. H.,Poon Leo L. M.ORCID,Hui David S. C.ORCID,Peiris MalikORCID

Funder

Food and Health Bureau of the Government of the Hong Kong Special Administrative Region | Health and Medical Research Fund

National Natural Science Foundation of China

Research Grants Council, University Grants Committee

Food and Health Bureau

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference20 articles.

1. Viana, R. et al. Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa. Nature (in the press). https://www.nature.com/articles/s41586-022-04411-y_reference.pdf

2. World Health Organization. Classification of Omicron (B.1.1.529): SARS-CoV-2 variant of concern 2021; https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern

3. Addetia, A. et al. Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate. J. Clin. Microbiol. 58, e02107-20 (2020).

4. McMahan, K. et al. Correlates of protection against SARS-CoV-2 in rhesus macaques. Nature 590, 630–634 (2021).

5. Khoury, D. S. et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat. Med. 27, 1205–1211 (2021).

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