Towards safe, non-viral therapeutic gene expression in humans
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg1577.pdf
Reference145 articles.
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3. Hollon, T. Researchers and regulators reflect on first gene therapy death. Nature Med. 6, 6 (2000).
4. Schroder, A. R. et al. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110, 521–529 (2002).
5. Woods, N. B. et al. Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis. Blood 101, 1284–1289 (2003).
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