ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets-Reference-Cited by-同舟云学术

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Published:2013-01-06 Issue:2 Volume:19 Page:202-208
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Souers Andrew J,Leverson Joel D,Boghaert Erwin R,Ackler Scott L,Catron Nathaniel D,Chen Jun,Dayton Brian D,Ding Hong,Enschede Sari H,Fairbrother Wayne J,Huang David C S,Hymowitz Sarah G,Jin Sha,Khaw Seong Lin,Kovar Peter J,Lam Lloyd T,Lee Jackie,Maecker Heather L,Marsh Kennan C,Mason Kylie D,Mitten Michael J,Nimmer Paul M,Oleksijew Anatol,Park Chang H,Park Cheol-Min,Phillips Darren C,Roberts Andrew W,Sampath Deepak,Seymour John F,Smith Morey L,Sullivan Gerard M,Tahir Stephen K,Tse Chris,Wendt Michael D,Xiao Yu,Xue John C,Zhang Haichao,Humerickhouse Rod A,Rosenberg Saul H,Elmore Steven W

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3048.pdf

Reference50 articles.

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3. Youle, R.J. & Strasser, A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 9, 47–59 (2008).

4. Tsujimoto, Y., Cossman, J., Jaffe, E. & Croce, C.M. Involvement of the bcl-2 gene in human follicular lymphoma. Science 228, 1440–1443 (1985).

5. Cleary, M.L., Smith, S.D. & Sklar, J. Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell 47, 19–28 (1986).

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