Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration-Reference-Cited by-同舟云学术

Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration

Published:2018-11 Issue:11 Volume:50 Page:1-14
ISSN:1226-3613
Container-title:Experimental & Molecular Medicine
language:en
Short-container-title:Exp Mol Med

Author:

Wang Jianle,Nisar Majid,Huang Chongan,Pan Xiangxiang,Lin Dongdong,Zheng Gang,Jin Haiming,Chen Deheng,Tian Naifeng,Huang Qianyu,Duan Yue,Yan Yingzhao,Wang Ke,Wu Congcong,Hu Jianing,Zhang Xiaolei^ORCID,Wang Xiangyang

Publisher

Springer Science and Business Media LLC

Subject

Clinical Biochemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://www.nature.com/articles/s12276-018-0173-3.pdf

Reference34 articles.

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2. Vergroesen, P. P. et al. Mechanics and biology in intervertebral disc degeneration: a vicious circle. Osteoarthr. Cartil. 23, 1057–1070 (2015).

3. Fontana, G., See, E. & Pandit, A. Current trends in biologics delivery to restore intervertebral disc anabolism. Adv. Drug Deliv. Rev. 84, 146–158 (2015).

4. Dimozi, A., Mavrogonatou, E., Sklirou, A. & Kletsas, D. Oxidative stress inhibits the proliferation, induces premature senescence and promotes a catabolic phenotype in human nucleus pulposus intervertebral disc cells. Eur. Cell Mater. 30, 89–102 (2015). discussion 3.

5. Chen, D. et al. Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo. Cell Death Dis. 7, e2441 (2016).

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