The 'evolvability' of promiscuous protein functions
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng1482.pdf
Reference30 articles.
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3. James, L.C. & Tawfik, D.S. Conformational diversity and protein evolution - a 60-year-old hypothesis revisited. Trends Biochem. Sci. 28, 361–368 (2003).
4. Arnold, F.H., Wintrode, P.L., Miyazaki, K. & Gershenson, A. How enzymes adapt: lessons from directed evolution. Trends Biochem. Sci. 26, 100–106 (2001).
5. Krebs, J.F., Ippolito, J.A., Christianson, D.W. & Fierke, C.A. Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II. J. Biol. Chem. 268, 27458–27466 (1993).
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