XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results

Author:

Cassidy J,Clarke S,Díaz-Rubio E,Scheithauer W,Figer A,Wong R,Koski S,Rittweger K,Gilberg F,Saltz L

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference18 articles.

1. Arkenau HT, Arnold D, Cassidy J, Diaz-Rubio E, Douillard JY, Hochster H, Martoni A, Grothey A, Hinke A, Schmiegel W, Schmoll HJ, Porschen R (2008) Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol 26: 5910–5917

2. Cassidy J, Clarke S, Diaz Rubio E, Scheithauer W, Figer A, Wong R, Koski S, Lichinitser M, Yang TS, Rivera F, Couture F, Sirzén F, Saltz L (2008a) A randomized phase III study of capecitabine plus oxaliplatin (XELOX) versus fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as first-line therapy for metastatic colorectal cancer. J Clin Oncol 26: 2006–2012

3. Cassidy J, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, Koski S, Sirzen F, Gilberg F, Saltz L (2008b) XELOX vs FOLFOX4: update of efficacy results from XELOX-1/NO16966, a randomized phase III trial of first-line treatment for patients (pts) with metastatic colorectal cancer (MCRC). Presented at the ASCO GI Cancers Symposium: Orlando, Florida, USA, 25–27 January (abstract 341)

4. Chu E, Schulman KL, Zelt S (2009) Costs associated with complications are lower with capecitabine than with 5-fluorouracil in patients with colorectal cancer. Cancer 115: 1412–1423

5. Comella P, Massidda B, Filippelli G, Farris A, Natale D, Barberis G, Maiorino L, Palmeri S, Condemi G, Southern Italy Cooperative Oncology Group (2009) Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401. J Cancer Res Clin Oncol 135: 217–226

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