2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas-Reference-Cited by-同舟云学术

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

Published:2012-01-26 Issue:4 Volume:18 Page:624-629
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Choi Changho,Ganji Sandeep K,DeBerardinis Ralph J,Hatanpaa Kimmo J,Rakheja Dinesh,Kovacs Zoltan,Yang Xiao-Li,Mashimo Tomoyuki,Raisanen Jack M,Marin-Valencia Isaac,Pascual Juan M,Madden Christopher J,Mickey Bruce E,Malloy Craig R,Bachoo Robert M,Maher Elizabeth A

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.2682.pdf

Reference31 articles.

1. Balss, J. et al. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 116, 597–602 (2008).

2. Yan, H. et al. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med 360, 765–773 (2009).

3. Dang, L. et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462, 739–744 (2009).

4. Figueroa, M.E. et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18, 553–567 (2010).

5. Christensen, B.C. et al. DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J. Natl. Cancer Inst. 103, 143–153 (2011).

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