Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Immunology and Microbiology,Microbiology,Infectious Diseases
Link
http://www.nature.com/articles/nrmicro1707.pdf
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5. Balzarini, J. Targeting the glycans of gp120: a novel approach aimed at the Achilles heel of HIV. Lancet Infect. Dis. 5, 726–731 (2005). The first extensive description of the new concept that CBAs may have a dual mechanism of antiviral action, including an immune response in addition to a direct inhibitory effect on virus entry.
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