Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia
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Published:2017-02-06
Issue:1
Volume:8
Page:
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ISSN:2041-1723
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Container-title:Nature Communications
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language:en
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Short-container-title:Nat Commun
Author:
Law Philip J.ORCID, Berndt Sonja I., Speedy Helen E., Camp Nicola J., Sava Georgina P., Skibola Christine F., Holroyd Amy, Joseph VijaiORCID, Sunter Nicola J., Nieters Alexandra, Bea Silvia, Monnereau Alain, Martin-Garcia David, Goldin Lynn R., Clot Guillem, Teras Lauren R., Quintela Inés, Birmann Brenda M., Jayne Sandrine, Cozen Wendy, Majid Aneela, Smedby Karin E., Lan Qing, Dearden Claire, Brooks-Wilson Angela R., Hall Andrew G., Purdue Mark P., Mainou-Fowler Tryfonia, Vajdic Claire M.ORCID, Jackson Graham H., Cocco Pierluigi, Marr Helen, Zhang Yawei, Zheng Tongzhang, Giles Graham G., Lawrence Charles, Call Timothy G., Liebow Mark, Melbye Mads, Glimelius Bengt, Mansouri Larry, Glenn Martha, Curtin Karen, Diver W Ryan, Link Brian K., Conde Lucia, Bracci Paige M., Holly Elizabeth A., Jackson Rebecca D., Tinker Lesley F., Benavente Yolanda, Boffetta Paolo, Brennan Paul, Maynadie Marc, McKay James, Albanes Demetrius, Weinstein Stephanie, Wang Zhaoming, Caporaso Neil E., Morton Lindsay M., Severson Richard K., Riboli Elio, Vineis Paolo, Vermeulen Roel C. H., Southey Melissa C., Milne Roger L.ORCID, Clavel Jacqueline, Topka Sabine, Spinelli John J., Kraft Peter, Ennas Maria Grazia, Summerfield Geoffrey, Ferri Giovanni M., Harris Robert J., Miligi Lucia, Pettitt Andrew R., North Kari E., Allsup David J.ORCID, Fraumeni Joseph F., Bailey James R., Offit Kenneth, Pratt Guy, Hjalgrim Henrik, Pepper Chris, Chanock Stephen J., Fegan Chris, Rosenquist Richard, de Sanjose Silvia, Carracedo Angel, Dyer Martin J. S., Catovsky Daniel, Campo EliasORCID, Cerhan James R., Allan James M., Rothman Nathanial, Houlston Richard, Slager Susan
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference62 articles.
1. Goldin, L. R., Pfeiffer, R. M., Li, X. & Hemminki, K. Familial risk of lymphoproliferative tumors in families of patients with chronic lymphocytic leukemia: results from the Swedish Family-Cancer Database. Blood 104, 1850–1854 (2004). 2. Di Bernardo, M. C. et al. A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat. Genet. 40, 1204–1210 (2008). 3. Crowther-Swanepoel, D. et al. Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. Nat. Genet. 42, 132–136 (2010). 4. Slager, S. L. et al. Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. Blood 117, 1911–1916 (2011). 5. Slager, S. L. et al. Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. Blood 120, 843–846 (2012).
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