Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm.4343.pdf
Reference56 articles.
1. Hsieh, J.J. et al. Renal cell carcinoma. Nat Rev Dis Primers 3, 17009 (2017).
2. Ghatalia, P. et al. Checkpoint inhibitors for the treatment of renal cell carcinoma. Curr. Treat. Options Oncol. 18, 7 (2017).
3. Choueiri, T.K. & Motzer, R.J. Systemic therapy for metastatic renal-cell carcinoma. N. Engl. J. Med. 376, 354–366 (2017).
4. Moore, L.E. et al. Von Hippel–Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors. PLoS Genet. 7, e1002312 (2011).
5. Nickerson, M.L. et al. Improved identification of von Hippel–Lindau gene alterations in clear cell renal tumors. Clin. Cancer Res. 14, 4726–4734 (2008).
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