Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease-Reference-Cited by-同舟云学术

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Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

Published:2002-06 Issue:6 Volume:8 Page:600-606
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Xu Jin,Kao Shyan-Yuan,Lee Frank J.S.,Song Weihong,Jin Lee-Way,Yankner Bruce A.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm0602-600.pdf

Reference30 articles.

1. Spillantini, M.G. et al. α-Synuclein in Lewy bodies. Nature 388, 839–840 (1997).

2. Olanow, C.W. & Tatton, W.G. Etiology and pathogenesis of Parkinson's disease. Ann. Rev. Neurosci. 22, 123–144 (1999).

3. Polymeropoulos, M.H. et al. Mutation in the α-Synuclein gene identified in families with Parkinson's disease. Science 276, 2045–2047 (1997).

4. Krüger, R. et al. Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nature Gen. 18, 106–108 (1998).

5. da Costa, C.A., Ancolio, K. & Checler, F. Wild-type but not Parkinson's disease-related ala-53→Thr mutant α-synuclein protects neuronal cells from apoptotic stimuli. J. Biol. Chem. 4, 24065–24069 (2000).

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