A new mission for an old anti-cancer drug: harnessing hepatocyte-specific metabolic pathways against liver tumors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
https://www.nature.com/articles/s41392-023-01513-5.pdf
Reference6 articles.
1. Shi, L. et al. SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nat. Cancer 4, 365–381 (2023).
2. Argemi, J., Ponz-Sarvise, M. & Sangro, B. Immunotherapies for hepatocellular carcinoma and intrahepatic cholangiocarcinoma: current and developing strategies. Adv. Cancer Res. 156, 367–413 (2022).
3. Wu, M. J., Shi, L., Merritt, J., Zhu, A. X. & Bardeesy, N. Biology of IDH mutant cholangiocarcinoma. Hepatology 75, 1322–1359 (2022).
4. Yeo, E. J. et al. YC-1: a potential anti-cancer drug targeting hypoxia-inducible factor 1. J. Natl. Cancer Inst. 95, 516–541 (2003).
5. Hempel, N., Wang, H., Lecluyse, E. L., Mcmanus, M. E. & Negishi, M. The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by Sp1 and GA binding protein. Mol. Pharmacol. 66, 1690–1701 (2004).
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