Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

Author:

Van Heek Margaret,Farley Constance,Compton Douglas S,Hoos Lizbeth,Alton Kevin B,Sybertz Edmund J,Davis Harry R

Publisher

Wiley

Subject

Pharmacology

Reference21 articles.

1. Review: first-pass metabolism by the gastrointestinal mucosa;BACK;Aliment. Pharmacol. Ther.,1987

2. The clinical development of a novel cholesterol absorption inhibitor;BERGMAN;XII International Symposium on Drugs Affecting Lipid Metabolism,1995

3. 2-Azetidinones as inhibitors of cholesterol absorption;BURNETT;J. Med. Chem.,1994

4. Effect of the cholesterol absorption inhibitor SCH48461 in combination with the HMG-CoA reductase inhibitor lovastatin in rabbits, dogs, and rhesus monkeys;DAVIS;Atherosclerosis,1994

5. The hypocholesterolemic activity of the potent cholesterol absorption inhibitor SCH58235 alone and in combination with HMG CoA reductase inhibitors (abstract);DAVIS;XII International Symposium on Drugs Affecting Lipid Metabolism (DALM),1995

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