Abstract
AbstractBioengineering and regenerative medicine strategies are promising for the treatment of vascular diseases. However, current limitations inhibit the ability of these approaches to be translated to clinical practice. Here we summarize some of the big bottlenecks that inhibit vascular regeneration in the disease applications of aortic aneurysms, stroke, and peripheral artery disease. We also describe the bottlenecks preventing three-dimensional bioprinting of vascular networks for tissue engineering applications. Finally, we describe emerging technologies and opportunities to overcome these challenges to advance vascular regeneration.
Funder
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
National Science Foundation
U.S. Department of Veterans Affairs
Tobacco Related Disease Research Program
Publisher
Springer Science and Business Media LLC
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