CryoTRANS: predicting high-resolution maps of rare conformations from self-supervised trajectories in cryo-EM
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s42003-024-06739-9.pdf
Reference50 articles.
1. Cao, E., Liao, M., Cheng, Y. & Julius, D. TRPV1 structures in distinct conformations reveal activation mechanisms. Nature 504, 113–118 (2013).
2. Kühlbrandt, W. The resolution revolution. Science 343, 1443–1444 (2014).
3. Bai, X.-c, McMullan, G. & Scheres, S. H. How cryo-EM is revolutionizing structural biology. Trends Biochem. Sci. 40, 49–57 (2015).
4. Cheng, Y. Single-particle cryo-EM—how did it get here and where will it go. Science 361, 876–880 (2018).
5. Zhu, J. et al. A minority of final stacks yields superior amplitude in single-particle cryo-em. Nat. Commun. 14, 7822 (2023).
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