How proteins move lipids and lipids move proteins
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/35080071.pdf
Reference97 articles.
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3. Higgins, J. A. & Pigott, C. A. Asymmetric distribution of phosphatidylethanolamine in the endoplasmic reticulum demonstrated using trinitrobenzenesulphonic acid as a probe. Biochim. Biophys. Acta 693, 151–158 (1982).
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5. Maeda, Y. et al. PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER. EMBO J. 20, 250–261 (2001).This paper pinpoints the substrate for this lumenal mannosyltransferase, glucoseaminyl (GlcN) α1-6-phosphoinositol, which is synthesized on the cytosolic side, as the actual lipid that translocates across the endoplasmic reticulum membrane during GPI-anchor synthesis.
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