Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells
Author:
Funder
Medical Research Council (MRC)
Wellcome Trust
Lister Institute of Preventive Medicine
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Infectious Diseases,Pharmacology,Immunology
Link
http://www.nature.com/articles/s41541-018-0071-7.pdf
Reference73 articles.
1. WHO. World Malaria Report. (2015).
2. Draper, S. J. et al. Recent advances in recombinant protein-based malaria vaccines. Vaccine 33, 7433–7443 (2015).
3. Halbroth, B. R. & Draper, S. J. Recent developments in malaria vaccinology. Adv. Parasitol. 88, 1–49 (2015).
4. Li, Y. et al. Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology. Sci. Rep. 6, 18848 (2016).
5. Brune, K. D. et al. Dual plug-and-display synthetic assembly using orthogonal reactive proteins for twin antigen immunization. Bioconjug. Chem. 28, 1544–1551 (2017).
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