Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia-Reference-Cited by-同舟云学术

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia

Published:2014-07-20 Issue:7519 Volume:513 Page:512-516
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Dail Monique,Wong Jason,Lawrence Jessica,O’Connor Daniel,Nakitandwe Joy,Chen Shann-Ching,Xu Jin,Lee Leslie B.,Akagi Keiko,Li Qing,Aster Jon C.,Pear Warren S.,Downing James R.,Sampath Deepak,Shannon Kevin

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13495.pdf

Reference33 articles.

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2. Gutierrez, A. et al. High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood 114, 647–650 (2009)

3. Tosello, V. & Ferrando, A. A. The NOTCH signaling pathway: role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy. Ther. Adv. Hematol. 4, 199–210 (2013)

4. Blackburn, J. S. et al. Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation. Cancer Cell 25, 366–378 (2014)

5. Piovan, E. et al. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Cancer Cell 24, 766–776 (2013)

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