MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool-Reference-Cited by-同舟云学术

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Published:2014-04-02 Issue:7495 Volume:508 Page:215-221
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Gad Helge,Koolmeister Tobias,Jemth Ann-Sofie,Eshtad Saeed,Jacques Sylvain A.,Ström Cecilia E.,Svensson Linda M.,Schultz Niklas,Lundbäck Thomas,Einarsdottir Berglind Osk,Saleh Aljona,Göktürk Camilla,Baranczewski Pawel,Svensson Richard,Berntsson Ronnie P.-A.,Gustafsson Robert,Strömberg Kia,Sanjiv Kumar,Jacques-Cordonnier Marie-Caroline,Desroses Matthieu,Gustavsson Anna-Lena,Olofsson Roger,Johansson Fredrik,Homan Evert J.,Loseva Olga,Bräutigam Lars,Johansson Lars,Höglund Andreas,Hagenkort Anna,Pham Therese,Altun Mikael,Gaugaz Fabienne Z.,Vikingsson Svante,Evers Bastiaan,Henriksson Martin,Vallin Karl S. A.,Wallner Olov A.,Hammarström Lars G. J.,Wiita Elisee,Almlöf Ingrid,Kalderén Christina,Axelsson Hanna,Djureinovic Tatjana,Puigvert Jordi Carreras,Häggblad Maria,Jeppsson Fredrik,Martens Ulf,Lundin Cecilia,Lundgren Bo,Granelli Ingrid,Jensen Annika Jenmalm,Artursson Per,Nilsson Jonas A.,Stenmark Pål,Scobie Martin,Berglund Ulrika Warpman,Helleday Thomas

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13181.pdf

Reference46 articles.

1. Druker, B. J. et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nature Med. 2, 561–566 (1996)

2. Bryant, H. E. et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose)polymerase. Nature 434, 913–917 (2005)

3. Farmer, H. et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434, 917–921 (2005)

4. Alexandrov, L. B. et al. Signatures of mutational processes in human cancer. Nature 500, 415–421 (2013)

5. Zhang, Y. et al. Redox control of the survival of healthy and diseased cells. Antioxid. Redox Signal. 15, 2867–2908 (2011)

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