Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
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Published:2018-11-26
Issue:12
Volume:21
Page:1656-1669
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ISSN:1097-6256
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Container-title:Nature Neuroscience
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language:en
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Short-container-title:Nat Neurosci
Author:
Walters Raymond K.ORCID, , Polimanti Renato, Johnson Emma C., McClintick Jeanette N., Adams Mark J.ORCID, Adkins Amy E., Aliev Fazil, Bacanu Silviu-Alin, Batzler Anthony, Bertelsen Sarah, Biernacka Joanna M., Bigdeli Tim B., Chen Li-Shiun, Clarke Toni-Kim, Chou Yi-Ling, Degenhardt Franziska, Docherty Anna R., Edwards Alexis C., Fontanillas PierreORCID, Foo Jerome C., Fox Louis, Frank JosefORCID, Giegling Ina, Gordon Scott, Hack Laura M., Hartmann Annette M., Hartz Sarah M., Heilmann-Heimbach Stefanie, Herms StefanORCID, Hodgkinson Colin, Hoffmann Per, Jan Hottenga Jouke, Kennedy Martin A.ORCID, Alanne-Kinnunen Mervi, Konte BettinaORCID, Lahti Jari, Lahti-Pulkkinen MariusORCID, Lai DongbingORCID, Ligthart Lannie, Loukola Anu, Maher Brion S., Mbarek HamdiORCID, McIntosh Andrew M.ORCID, McQueen Matthew B., Meyers Jacquelyn L., Milaneschi Yuri, Palviainen TeemuORCID, Pearson John F., Peterson Roseann E., Ripatti Samuli, Ryu Euijung, Saccone Nancy L., Salvatore Jessica E., Sanchez-Roige Sandra, Schwandt Melanie, Sherva Richard, Streit FabianORCID, Strohmaier Jana, Thomas Nathaniel, Wang Jen-Chyong, Webb Bradley T., Wedow RobbeeORCID, Wetherill Leah, Wills Amanda G., Boardman Jason D., Chen Danfeng, Choi Doo-Sup, Copeland William E., Culverhouse Robert C., Dahmen Norbert, Degenhardt Louisa, Domingue Benjamin W., Elson Sarah L., Frye Mark A., Gäbel Wolfgang, Hayward CarolineORCID, Ising Marcus, Keyes Margaret, Kiefer Falk, Kramer JohnORCID, Kuperman Samuel, Lucae Susanne, Lynskey Michael T., Maier Wolfgang, Mann Karl, Männistö Satu, Müller-Myhsok Bertram, Murray Alison D., Nurnberger John I., Palotie Aarno, Preuss Ulrich, Räikkönen Katri, Reynolds Maureen D, Ridinger Monika, Scherbaum Norbert, Schuckit Marc A., Soyka Michael, Treutlein Jens, Witt StephanieORCID, Wodarz Norbert, Zill Peter, Adkins Daniel E., Boden Joseph M., Boomsma Dorret I., Bierut Laura J., Brown Sandra A.ORCID, Bucholz Kathleen K., Cichon Sven, Costello E. Jane, de Wit Harriet, Diazgranados Nancy, Dick Danielle M., Eriksson Johan G., Farrer Lindsay A., Foroud Tatiana M., Gillespie Nathan A., Goate Alison M.ORCID, Goldman David, Grucza Richard A., Hancock Dana B., Harris Kathleen Mullan, Heath Andrew C., Hesselbrock Victor, Hewitt John K., Hopfer Christian J., Horwood John, Iacono William, Johnson Eric O., Kaprio Jaakko A.ORCID, Karpyak Victor M., Kendler Kenneth S., Kranzler Henry R.ORCID, Krauter Kenneth, Lichtenstein PaulORCID, Lind Penelope A.ORCID, McGue Matt, MacKillop JamesORCID, Madden Pamela A. F., Maes Hermine H., Magnusson PatrikORCID, Martin Nicholas G.ORCID, Medland Sarah E.ORCID, Montgomery Grant W.ORCID, Nelson Elliot C., Nöthen Markus M., Palmer Abraham A., Pedersen Nancy L., Penninx Brenda W. J. H., Porjesz Bernice, Rice John P., Rietschel MarcellaORCID, Riley Brien P., Rose Richard, Rujescu Dan, Shen Pei-Hong, Silberg Judy, Stallings Michael C., Tarter Ralph E., Vanyukov Michael M., Vrieze ScottORCID, Wall Tamara L., Whitfield John B.ORCID, Zhao Hongyu, Neale Benjamin M.ORCID, Gelernter JoelORCID, Edenberg Howard J.ORCID, Agrawal ArpanaORCID
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Reference74 articles.
1. World Health Organization. Global Status Report on Alcohol and Health, 2014 (WHO Press, Geneva, Switzerland, 2014). 2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (APA Publishing, Washington DC, USA, 2000). 3. Hasin, D. S., Stinson, F. S., Ogburn, E. & Grant, B. F. Prevalence, correlates, disability, and comorbidity of DSM-IV alcohol abuse and dependence in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch. Gen. Psychiatry 64, 830–842 (2007). 4. Dawson, D. A., Grant, B. F., Stinson, F. S. & Chou, P. S. Estimating the effect of help-seeking on achieving recovery from alcohol dependence. Addiction 101, 824–834 (2006). 5. Verhulst, B., Neale, M. C. & Kendler, K. S. The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies. Psychol. Med. 45, 1061–1072 (2015).
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