Developmental trajectory of transmission speed in the human brain

Author:

van Blooijs DorienORCID,van den Boom Max A.ORCID,van der Aar Jaap F.ORCID,Huiskamp Geertjan M.,Castegnaro Giulio,Demuru Matteo,Zweiphenning Willemiek J. E. M.,van Eijsden Pieter,Miller Kai J.ORCID,Leijten Frans S. S.ORCID,Hermes DoraORCID

Abstract

AbstractThe structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.

Funder

EpilepsyNL, NEF17-07

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

UMC Utrecht Alexandre Suerman MD/PhD Stipendium 2015

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

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