Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling-Reference-Cited by-同舟云学术

Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling

Published:2005-10-23 Issue:11 Volume:11 Page:1197-1204
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Kusano Kengo F,Pola Roberto,Murayama Toshinori,Curry Cynthia,Kawamoto Atsuhiko,Iwakura Atsushi,Shintani Satoshi,Ii Masaaki,Asai Jun,Tkebuchava Tengiz,Thorne Tina,Takenaka Hideya,Aikawa Ryuichi,Goukassian David,von Samson Patrick,Hamada Hiromichi,Yoon Young-sup,Silver Marcy,Eaton Elizabeth,Ma Hong,Heyd Lindsay,Kearney Marianne,Munger William,Porter Jeffery A,Kishore Raj,Losordo Douglas W

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1313.pdf

Reference39 articles.

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2. Isner, J.M. & Losordo, D.W. Therapeutic angiogenesis for heart failure. Nat. Med. 5, 491–492 (1999).

3. Losordo, D.W. et al. Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circulation 105, 2012–2018 (2002).

4. Fortuin, F.D. et al. One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients. Am. J. Cardiol. 52, 436–439 (2003).

5. Vale, P.R. et al. Randomized, single-blind, placebo-controlled pilot study of catheter- based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia. Circulation 103, 2138–2143 (2001).

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