Population genetic structure of variable drug response-Reference-Cited by-同舟云学术

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Population genetic structure of variable drug response

Published:2001-10-29 Issue:3 Volume:29 Page:265-269
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Wilson James F.,Weale Michael E.,Smith Alice C.,Gratrix Fiona,Fletcher Benjamin,Thomas Mark G.,Bradman Neil,Goldstein David B.

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng761z.pdf

Reference21 articles.

1. Weber, W.W. Pharmacogenetics (Oxford University Press, Oxford, 1997).

2. Evans, W.E. & Relling, M.V. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487–491 (1999).

3. Gough, A.C. et al. Identification of the primary gene defect at the cytochrome P450 CYP2D locus. Nature 347, 773–776 (1990).

4. Kagimoto, M., Heim, M., Kagimoto, K., Zeugin, T. & Meyer, U.A. Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes. J. Biol. Chem. 265, 17209–17214 (1990).

5. Blum, M., Demierre, A., Grant, D.M., Heim, M. & Meyer, U.A. Molecular mechanism of slow acetylation of drugs and carcinogens in humans. Proc. Natl Acad. Sci. USA 88, 5237–5241 (1991).

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