The dTAG system for immediate and target-specific protein degradation-Reference-Cited by-同舟云学术

The dTAG system for immediate and target-specific protein degradation

Published:2018-03-26 Issue:5 Volume:14 Page:431-441
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Nabet Behnam^ORCID,Roberts Justin M.^ORCID,Buckley Dennis L.,Paulk Joshiawa,Dastjerdi Shiva,Yang Annan,Leggett Alan L.,Erb Michael A.^ORCID,Lawlor Matthew A.,Souza Amanda,Scott Thomas G.,Vittori Sarah,Perry Jennifer A.,Qi Jun,Winter Georg E.,Wong Kwok-Kin,Gray Nathanael S.^ORCID,Bradner James E.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/s41589-018-0021-8.pdf

Reference55 articles.

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3. Zengerle, M., Chan, K. H. & Ciulli, A. Selective small molecule induced degradation of the BET bromodomain protein BRD4. ACS Chem. Biol. 10, 1770–1777 (2015).

4. Winter, G. E. et al. BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment. Mol. Cell 67, 5–18.e19 (2017).

5. Bondeson, D. P. et al. Catalytic in vivo protein knockdown by small-molecule PROTACs. Nat. Chem. Biol. 11, 611–617 (2015).

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