AAV Empty Capsids: For Better or for Worse?
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference6 articles.
1. Adenovirus-associated virus vector-mediated gene transfer in hemophilia B;Nathwani;N Engl J Medicine,2011
2. Good manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trial;Allay;Hum Gene Ther,2011
3. Overcoming preexisting humoral immunity to AAV using capsid decoys;Mingozzi;Science Transl Med,2013
4. Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors;Hoffman;Mol Ther,2013
5. Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects;Gao;Mol Ther Methods Clin Dev,2013
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2. Methodological Validation of Sedimentation Velocity Analytical Ultracentrifugation Method for Adeno-Associated Virus and Collaborative Calibration of System Suitability Substance;Human Gene Therapy;2024-06-01
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4. Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol;Journal of Visualized Experiments;2024-04-05
5. Analytical characterization of full, intermediate, and empty AAV capsids;Gene Therapy;2024-02-19
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