Metabolic syndrome: from epidemiology to systems biology
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg2468.pdf
Reference133 articles.
1. Reaven, G. M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37, 1595–1607 (1988). The first definition of MetSyn as an entity, defined by the clustering of abnormalities having insulin resistance as an underlying cause. Although the specific definition continues to evolve, the major insights presented here have remained important.
2. Eckel, R. H., Grundy, S. M. & Zimmet, P. Z. The metabolic syndrome. Lancet 365, 1415–1428 (2005).
3. Kahn, S. E., Hull, R. L. & Utzschneider, K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444, 840–846 (2006).
4. King, R. A., Rotter, J. I. & Motulsky, A. G. The Genetic Basis of Common Disease (Oxford University Press, New York, 2002).
5. Lazar, M. A. How obesity causes diabetes: not a tall tale. Science 307, 373–375 (2005).
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