Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
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Published:2014-06-22
Issue:8
Volume:46
Page:826-836
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Arking Dan E, , Pulit Sara L, Crotti Lia, van der Harst Pim, Munroe Patricia B, Koopmann Tamara T, Sotoodehnia Nona, Rossin Elizabeth J, Morley Michael, Wang XinchenORCID, Johnson Andrew D, Lundby AliciaORCID, Gudbjartsson Daníel F, Noseworthy Peter A, Eijgelsheim Mark, Bradford Yuki, Tarasov Kirill VORCID, Dörr Marcus, Müller-Nurasyid Martina, Lahtinen Annukka M, Nolte Ilja M, Smith Albert Vernon, Bis Joshua C, Isaacs Aaron, Newhouse Stephen J, Evans Daniel S, Post Wendy S, Waggott Daryl, Lyytikäinen Leo-Pekka, Hicks Andrew AORCID, Eisele Lewin, Ellinghaus David, Hayward Caroline, Navarro Pau, Ulivi SheilaORCID, Tanaka Toshiko, Tester David J, Chatel Stéphanie, Gustafsson Stefan, Kumari Meena, Morris Richard W, Naluai Åsa T, Padmanabhan Sandosh, Kluttig Alexander, Strohmer Bernhard, Panayiotou Andrie G, Torres Maria, Knoflach Michael, Hubacek Jaroslav A, Slowikowski KamilORCID, Raychaudhuri Soumya, Kumar Runjun D, Harris Tamara B, Launer Lenore J, Shuldiner Alan R, Alonso Alvaro, Bader Joel SORCID, Ehret Georg, Huang Hailiang, Kao W H Linda, Strait James B, Macfarlane Peter W, Brown Morris, Caulfield Mark J, Samani Nilesh J, Kronenberg Florian, Willeit Johann, Smith J Gustav, Greiser Karin H, Meyer zu Schwabedissen Henriette, Werdan Karl, Carella Massimo, Zelante Leopoldo, Heckbert Susan R, Psaty Bruce M, Rotter Jerome I, Kolcic Ivana, Polašek Ozren, Wright Alan F, Griffin Maura, Daly Mark J, Arnar David O, Hólm Hilma, Thorsteinsdottir Unnur, Denny Joshua C, Roden Dan M, Zuvich Rebecca L, Emilsson Valur, Plump Andrew S, Larson Martin G, O'Donnell Christopher J, Yin Xiaoyan, Bobbo Marco, D'Adamo Adamo P, Iorio Annamaria, Sinagra Gianfranco, Carracedo Angel, Cummings Steven R, Nalls Michael A, Jula Antti, Kontula Kimmo K, Marjamaa Annukka, Oikarinen Lasse, Perola Markus, Porthan Kimmo, Erbel Raimund, Hoffmann Per, Jöckel Karl-Heinz, Kälsch Hagen, Nöthen Markus M, den Hoed Marcel, Loos Ruth J F, Thelle Dag S, Gieger Christian, Meitinger Thomas, Perz Siegfried, Peters Annette, Prucha Hanna, Sinner Moritz F, Waldenberger Melanie, de Boer Rudolf A, Franke Lude, van der Vleuten Pieter A, Beckmann Britt Maria, Martens Eimo, Bardai Abdennasser, Hofman Nynke, Wilde Arthur A M, Behr Elijah R, Dalageorgou Chrysoula, Giudicessi John RORCID, Medeiros-Domingo Argelia, Barc Julien, Kyndt Florence, Probst Vincent, Ghidoni Alice, Insolia Roberto, Hamilton Robert M, Scherer Stephen W, Brandimarto Jeffrey, Margulies Kenneth, Moravec Christine E, Greco M Fabiola del, Fuchsberger Christian, O'Connell Jeffrey R, Lee Wai K, Watt Graham C M, Campbell Harry, Wild Sarah H, El Mokhtari Nour E, Frey Norbert, Asselbergs Folkert W, Leach Irene Mateo, Navis Gerjan, van den Berg Maarten P, van Veldhuisen Dirk J, Kellis Manolis, Krijthe Bouwe P, Franco Oscar H, Hofman Albert, Kors Jan A, Uitterlinden André G, Witteman Jacqueline C M, Kedenko Lyudmyla, Lamina Claudia, Oostra Ben A, Abecasis Gonçalo R, Lakatta Edward G, Mulas Antonella, Orrú Marco, Schlessinger David, Uda Manuela, Markus Marcello R P, Völker Uwe, Snieder Harold, Spector Timothy D, Ärnlöv Johan, Lind Lars, Sundström Johan, Syvänen Ann-Christine, Kivimaki Mika, Kähönen Mika, Mononen Nina, Raitakari Olli T, Viikari Jorma S, Adamkova Vera, Kiechl Stefan, Brion Maria, Nicolaides Andrew N, Paulweber Bernhard, Haerting Johannes, Dominiczak Anna F, Nyberg Fredrik, Whincup Peter H, Hingorani Aroon D, Schott Jean-Jacques, Bezzina Connie R, Ingelsson Erik, Ferrucci Luigi, Gasparini Paolo, Wilson James F, Rudan IgorORCID, Franke Andre, Mühleisen Thomas W, Pramstaller Peter P, Lehtimäki Terho J, Paterson Andrew D, Parsa Afshin, Liu Yongmei, van Duijn Cornelia M, Siscovick David S, Gudnason Vilmundur, Jamshidi Yalda, Salomaa Veikko, Felix Stephan B, Sanna Serena, Ritchie Marylyn DORCID, Stricker Bruno H, Stefansson Kari, Boyer Laurie A, Cappola Thomas P, Olsen Jesper V, Lage Kasper, Schwartz Peter J, Kääb Stefan, Chakravarti Aravinda, Ackerman Michael J, Pfeufer Arne, de Bakker Paul I W, Newton-Cheh Christopher, , , ,
Publisher
Springer Science and Business Media LLC
Reference52 articles.
1. Schwartz, P.J., Crotti, L. & Insolia, R. Long-QT syndrome: from genetics to management. Circ. Arrhythm. Electrophysiol. 5, 868–877 (2012). 2. Newton-Cheh, C. et al. QT interval is a heritable quantitative trait with evidence of linkage to chromosome 3 in a genome-wide linkage analysis: The Framingham Heart Study. Heart Rhythm 2, 277–284 (2005). 3. Newton-Cheh, C. et al. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat. Genet. 41, 399–406 (2009). 4. Pfeufer, A. et al. Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat. Genet. 41, 407–414 (2009). 5. Arking, D.E. et al. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat. Genet. 38, 644–651 (2006).
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